A mass shooting at an Orlando nightclub early Sunday in which 50 people died, including the gunman, marks yet another brutal rampage in U.S. history.
Police say the tragedy began when three officers engaged in a gunfight with a suspect outside Pulse, a gay nightclub. Officer stormed the club after a hostage situation. The incident was being investigated as a possible act of terrorism.
Photos | 50 dead in Orlando shooting
PHOTOS: Mass shooting at Orlando nightclub
Here are some of the deadliest rampages in U.S. history:
• April 16, 2007: Seung Hui Cho, a 23-year-old student, went on a shooting spree at Virginia Tech in Blacksburg, Va., killing 32 people, before killing himself.
• Dec. 14, 2012: Adam Lanza, 20, gunned down 20 children and six adults at Sandy Hook Elementary School before killing himself.
• Oct. 16, 1991: George Hennard, 35, crashed his pickup through the wall of Luby's Cafeteria in Killeen, Texas. He shot and killed 23 people before committing suicide.
• July 18, 1984: James Huberty, 41, gunned down 21 adults and children at a McDonald's in San Ysidro, Calif., before being killed by police.
• Aug. 1, 1966: Charles Joseph Whitman, a former U.S. Marine, shot and killed 16 people from a university tower at the University of Texas in Austin before being shot by police.
• Aug. 20, 1986: A part-time mail carrier, Patrick Henry Sherrill, shot and killed 14 postal workers in Edmund, Okla., before killing himself.
• Dec. 2, 2015: Syed Farook and Tashfeen Malik, a married couple living in Redlands, Calif., opened fire at a San Bernardino County Department of Public Health training event and holiday party, killing 14 people and injuring 22 in a matter of minutes. Farook, an American-born U.S. citizen of Pakistani descent, worked at the health department. Malik had pledged allegiance to the Islamic State in a Facebook post before the shooting.
• Nov. 5, 2009: U.S. Army Maj. Nidal Hasan fatally shot 13 people and injured 30 others at Fort Hood near Killeen, Texas. Hasan, a psychiatrist, appeared to have been radicalized by an Islamic cleric. He was convicted and sentenced to death.
• Sept. 16, 2013: Gunman Aaron Alexis, 34, fatally shot 12 people and injured three others at the headquarters of the Naval Sea Systems Command in Washington, D.C. He was later killed by police.
• July 20, 2012: James Holmes gunned down 12 people in an Aurora, Colo., movie theater. Last year he was convicted of first-degree murder and attempted murder and sentenced to 12 consecutive life sentences plus 3,318 years without parole.
• Oct. 1, 2015: Christopher Harper-Mercer, a 26-year-old student at Umpqua Community College near Roseburg, Ore., shot an assistant professor and eight students in a classroom. After a shootout with police, he committed suicide.
• June 18, 2015: A gunman opened fire at a weekly Bible study at the Emanuel African Methodist Episcopal Church in Charleston, S.C. Nine people were killed, including the pastor Clementa Pinckney; a 10th victim survived. The morning after the attack police arrested a suspect, Dylann Roof, 21, who said he wanted to start a race war. Laywers for Roof, who was charged in the rampage, last week filed papers seeking to waive his right to a jury trial.
• July 16, 2015: Muhammad Youssef Abdulazeez opened fire on two military installations in Chattanooga, Tenn. The first was a drive-by shooting at a recruiting center; the second was at a U.S. Navy Reserve center. Four Marines and a Navy sailor died; a Marine recruit officer and a police offer were wounded. Abdulazeez was killed by police in a gunfight.
• Nov. 27, 2015: A gunman attacked a Planned Parenthood clinic in Colorado Springs, Colo., killing a police officer and two civilians and injuring nine others. Robert Lewis Dear was taken into custody after a five-hour standoff and charged with first-degree murder.