BIRMINGHAM, Ala. -- Birmingham mayor William Bell told CNN Wednesday morning that both the pilot and co-pilot of a UPS Airbus A300 were killed in a crash near the Birmingham-Shuttlesworth International Airport.
The FAA said the jet, UPS Flight 1354 from Louisville to Birmingham, crashed on approach to the airport around 5:45 a.m. Atlanta time.
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FAA spokeswoman Kathleen Bergen said the crash happened about a half-mile north of the runway.
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Toni Herrera-Bast, a spokeswoman for Birmingham's airport authority, says there are no homes in the immediate area of the crash.
Birmingham NBC station WVTM said witnesses reported hearing "a large boom" followed by several explosions.
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According to UPS, the pilot and co-pilot were the only two people on board at the time of the crash.
NTSB "go-teams" from Atlanta and Washington are en-route to the crash scene for their investigation.
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UPS has released a statement concerning the crash:
UPS has been notified of an aircraft incident involving Flight 1354, an Airbus A300 flying from Louisville, KY to Birmingham, AL.
At this time, we are still determining the details of the incident. We will release more information as it becomes available. As we work through this difficult situation, we ask for your patience, and that you keep those involved in your thoughts and prayers.
The UPS Corporate and Regional Headquarters is based in Atlanta, on Glenlake Parkway NE.
NTSB said as of 5:30 p.m., the tail section of plane was still smoldering so they had not yet retrieved the black box.
(NBC News & CNN contributed to this report.)