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Philadelphia, PA (Sports Network) - Villanova used 15 points from Ryan Arcidiacono and a stifling overall defensive effort to hand reeling Louisville a 73-64 loss in a Big East matchup from the Wells Fargo Center.

JayVaughn Pinkston added 13 points and seven rebounds for the Wildcats (12-7, 3-3 Big East), who outscored the fifth-ranked Cardinals 20-11 over the final four minutes to end a streak of three straight conference losses.

After falling out of the top spot in the polls following Saturday's narrow home loss to Syracuse, Louisville (16-3, 4-2) were held to just 39.7 percent shooting from the field and committed 17 turnovers to receive a second straight setback following an 11-game win streak.

Wayne Blackshear paced the Cardinals with 17 points, while Peyton Siva netted 15 along with 11 assists and Gorgui Dieng compiled 10 points and 10 rebounds.