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Cleveland, OH (Sports Network) - Carlos Santana's solo home run in the 10th inning lifted the Cleveland Indians past the Chicago White Sox, 6-5, in the third contest of a four-game series from Progressive Field.

Santana led off the bottom of the 10th by blasting a full-count fastball from Dylan Axelrod (3-7) into the right-field seats for the Indians' league-leading ninth walk-off win of the year.

Chris Perez (4-1) pitched a perfect top of the 10th to earn the victory for the Indians, winners of a season-high seven straight games.

Jason Kipnis and Santana each drove in two runs while Michael Brantley and Michael Bourn each added an RBI for Cleveland, which has won seven consecutive meetings against the White Sox as well.

Jeff Keppinger drove in two runs while Alexei Ramirez, Alex Rios and Adam Dunn added an RBI each for the White Sox, who have dropped six in a row.