Get your game face on!

It's time to play a rapidfire game of '5 Second Rule' with Will & Grace's Megan Mullally and Ellen.

Did you know the two have known each other for 30 years? Mullally and DeGeneres lived just a block away from each other in Los Angeles at the start of their careers.

Preview Ellen's challenge against her old friend below and watch in full weekdays at 4:00 on 11Alive.

Megan Mullally Plays '5 Second Rule'