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Read Sen. Johnny Isakson's resignation letter to Gov. Brian Kemp

The long-serving Georgia senator announced Wednesday he would leave his seat at the end of the year.

ATLANTA — Georgia Sen. Johnny Isakson announced Wednesday he is resigning at the end of the year, citing ongoing health concerns.

He said that he will not be able to continue to do the job “in the manner the citizens of Georgia deserve."

RELATED: Sen. Johnny Isakson to resign at end of year

Below, read the full resignation letter Isakson sent to Georgia Gov. Brian Kemp:

Isakson, 74, was diagnosed with Parkinson’s disease in 2013. In July, Isakson fell in his D.C. apartment and suffered four fracture ribs and a torn rotator cuff. On Monday, Isakson underwent surgery at WellStar Kennestone Hospital in Marietta to remove a 2-centimeter renal cell carcinoma from one of his kidneys.

“In my 40 years in elected office, I have always put my constituents and my state of Georgia first. With the mounting health challenges I am facing, I have concluded that I will not be able to do the job over the long term in the manner the citizens of Georgia deserve," Isakson said. "It goes against every fiber of my being to leave in the middle of my Senate term, but I know it’s the right thing to do on behalf of my state."

In 2016, Isakson won re-election with 54% of the vote and became the first Republican in Georgia to be elected to a third term in the U.S. Senate. 

After more than three decades in the real estate business, Isakson became the only elected official in Georgia to serve in the Georgia House, the Georgia Senate, the U.S. House and the U.S. Senate.